abstract：:The binding of Cu(II), Zn(II), Ni(II), and Cd(II) to protein components in serum, placenta, kidney, and urine was investigated at physiological pH, using radioisotopes as tracers. All the four metals were bound to albumin and other macromolecules in serum. However, small amounts were also bound to low molecular weight...

journal_title：Biological trace element research

authors： Sarkar B

更新日期：1989-07-01 00:00:00

abstract：:The metabolism of 203Hg-labeled methylmercury chloride (MeHg) has been studied in rabbits and hamsters. Rabbits were administered 1.6 mumols MeHgCl/kg bw intravenously, and hamsters 40 mumols/kg bw orally. Urine and feces were collected daily and groups of four animals killed after 1 h, 1 d, or 7 d. The concentration ...

journal_title：Biological trace element research

authors： Petersson K,Dock L,Vahter M

更新日期：1989-07-01 00:00:00

abstract：:Arsenite has been known for half a century to have a protective effect against selenium poisoning. Paradoxically, arsenite inhibits the conversion of inorganic selenium salts to methylated excretory products, although methylation has long been regarded as a detoxification mechanism for selenium. Moreover, there is evi...

journal_title：Biological trace element research

authors： Kraus RJ,Ganther HE

更新日期：1989-04-01 00:00:00

abstract：:The effects of selenium were investigated on three human colon cancer cell lines: Caco 2, HRT 18, and HT 29. At low concentrations (10-100 nM), selenium stimulated cell growth in serum-free medium. Thus, selenium is an essential trace element for cell proliferation. At higher concentrations, selenium inhibited cell gr...

journal_title：Biological trace element research

authors： Nano JL,Czerucka D,Menguy F,Rampal P

更新日期：1989-04-01 00:00:00

abstract：:The solubility of both free and low molecular weight ligand complexed calcium, magnesium, and zinc in skimmed human and bovine milks over intestinal luminal pH ranges (approximately 3-7) was measured using ultrafiltration techniques. Some of the experimental difficulties associated with the separation of labile metal ...

journal_title：Biological trace element research

authors： Brushmiller JG,Ames RW,Jacobs FA,Nelson LS

更新日期：1989-01-01 00:00:00

abstract：:Trace elements can influence dental health, possibly by altering tooth resistance during preeruptive development. Therefore, it was investigated whether lead and fluoride would be incorporated into the calcifying matrices or the cellular parts of tooth germs in vitro. Using laser microprobe mass analysis, the localiza...

journal_title：Biological trace element research

authors： Vandeputte DF,Ameloot PC,Cleymaet R,Coomans D,Van Grieken RE

更新日期：1989-01-01 00:00:00

abstract：:The effects of nutritional copper deficiency on carrageenin edema in the rat were investigated with emphasis on studying the correlation between the degree of copper deficiency and the degree of edema. Carrageenin paw edema in both copper-sufficient and copper-deficient groups of rats was compared after either 20, 40,...

journal_title：Biological trace element research

authors： Kishore V,Wokocha B,Fourcade L

更新日期：1989-01-01 00:00:00

abstract：:The authors present a simple and rapid method for assaying ultrafilterable copper (Cu UF) and albumin-bound copper (Cu ALB). It is based on the ultrafiltration of serum in the presence of ethylenediaminetetraacetic acid (EDTA), used to prevent adsorption on the membranes. EDTA at 0.4 g/L has no effect on the equilibri...

journal_title：Biological trace element research

authors： Favier A,Ruffieux D

更新日期：1988-12-01 00:00:00

abstract：:The molecular localization of maternal and fetal zinc and copper metalloproteins in diabetic and control rats was studied. Compared to controls, liver and kidneys of diabetic dams showed an increased concentration of zinc and copper that was associated with metallothionein. In contrast, fetuses of diabetic dams had lo...

journal_title：Biological trace element research

authors： Uriu-Hare JY,Stern JS,Keen CL

更新日期：1988-12-01 00:00:00

abstract：:The concentrations of 17 elements in the nail and hair of 117 subjects from a nonindustrialized environment were determined by instrumental neutron activation analysis (INAA). A new method of statistical treatment that allows for more meaningful use of detection limit values was used to process the concentration data....

journal_title：Biological trace element research

authors： Vance DE,Ehmann WD,Markesbery WR

更新日期：1988-09-01 00:00:00

abstract：:An "anti-oxidant cocktail" consisting of betacarotene, vitamins B6, C, E, zinc, and selenium or corresponding placebos were given for one y as daily dietary supplements to 45 elderly residents of a nursing home. Initially, the serum TBA reactant levels were higher (2.7 +/- 0.7 mumol/L) than those of an ad hoc control ...

journal_title：Biological trace element research

authors： Tolonen M,Sarna S,Halme M,Tuominen SE,Westermarck T,Nordberg UR,Keinonen M,Schrijver J

更新日期：1988-09-01 00:00:00

abstract：:The growth of the protozoan Blepherisma is stimulated by Lanthanum (La) at concentrations as low as 0.32 ppm. In mice Yttrium (Y) and Ytterbium (Yb) are absorbed, accumulated, and metabolized. Both rare earth elements (RE) exhibit a high affinity for teeth and bones, accumulation occurs and metabolism is slow. In the ...

journal_title：Biological trace element research

authors： Zhang WD,Li FQ,Zhang XY,Chen Y

更新日期：1988-09-01 00:00:00

abstract：:The effect of zinc deficiency on calmodulin function was investigated by assessing the in vivo activity of two calmodulin regulated enzymes, adenosine 3',5'-monophosphate (c-AMP) and guanosine 3',5'-monophosphate (c-GMP) phosphodiesterase (PDE) in several rat tissues. Enzymatic activities in brain, heart, and testis o...

journal_title：Biological trace element research

authors： Law JS,McBride SA,Graham S,Nelson NR,Slotnick BM,Henkin RI

更新日期：1988-08-01 00:00:00

abstract：:The tissue distribution of 14 elements was simultaneously determined in rats 28 d after hypophysectomy (HPY), thyroparathyroidectomy (TPTY), adrenalectomy (ADY), and castration (CTN). The elements Na, K, Ca, Mg, Fe, S, P, Rb, Sr, Mn, Cu, and Zn were investigated in whole blood, plasma, brain, liver, kidney, heart, ske...

journal_title：Biological trace element research

authors： LeBlondel G,Ducouret C,Allain P

更新日期：1988-07-01 00:00:00

abstract：:The selenium levels and the glutathione peroxidase activity GSH-PX of whole blood and of erythrocytes, respectively, were determined in 139 normal Danes and related to sex and smoking habits. No differences were found in relation to sex apart from a higher GSH-PX activity of females when assayed with tertiary butyl hy...

journal_title：Biological trace element research

authors： Clausen J,Nielsen SA

更新日期：1988-01-01 00:00:00

abstract：:The selenium concentrations were determined in liver, kidney, skeletal muscle, heart, brain, prostate, testis, bile, lung, and spleen of German traffic accident victims. In addition, the nitrogen and phosphorus contents were determined in the same organs and tissues. On a per-weight unit basis, the highest selenium co...

journal_title：Biological trace element research

authors： Oster O,Schmiedel G,Prellwitz W

更新日期：1988-01-01 00:00:00

abstract：:The binding of selenite, the form of selenium used in the treatment of Keshan disease, to plasma proteins and the role of erythrocytes in this process have been studied. The experiments were carried out by incubating 75Se as selenite with plasma and whole blood in vitro (human and rat) and in vivo (rat) and subsequent...

journal_title：Biological trace element research

authors： Mas A,Jiang JY,Sarkar B

更新日期：1988-01-01 00:00:00

abstract：:Studies were performed on adult and fetal rats receiving either a zinc-deficient (<0.5 ppm) diet and/or ethanol (20%) throughout pregnancy. Liver zinc levels were depressed in fetuses exposed toin utero zinc deficiency, but brain zinc levels were unchanged. Ethanol had no effect on the concentration of zinc in the sev...

journal_title：Biological trace element research

authors： Dreosti IE,Partick EJ

更新日期：1987-12-01 00:00:00

abstract：:Trientine((R)) is not an effective drug for the treatment of intractable hand dermatitis in nickel-sensitive patients. In a controlled, double-blind study this chelator, on oral administration, failed to stimulate nickel excretion. Early morning urine samples from two groups of nine patients were analyzed by atomic ab...

journal_title：Biological trace element research

authors： McMaster D,Burrows D,Eedy DJ,Love AH

更新日期：1987-10-01 00:00:00

abstract：:Results from several medical investigations carried out using the Oxford scanning proton microprobe are presented, including maps of the hepatic copper-distribution in primary biliary cirrhosis and maps of the iron distribution in primary hemochromatosis. Preliminary studies of human nervous tissue reveal that morphol...

journal_title：Biological trace element research

authors： Vaux DJ,Grime GW,Watt F

更新日期：1987-08-01 00:00:00

abstract：:In vivo X-ray fluorescence (XRF) techniques were used for biological monitoring of lead, cadmium, and mercury. Lead accumulates in bone, the level of which may thus be used for monitoring of exposure. However, there was no close association between lead levels in bone and exposure time, partly because of differences i...

journal_title：Biological trace element research

authors： Skerfving S,Christoffersson JO,Schütz A,Welinder H,Spång G,Ahlgren L,Mattsson S

更新日期：1987-08-01 00:00:00

abstract：:Both thermal and epithermal neutron activation analyses have been employed to determine chromium and nickel in lung tissue and arsenic in urine. Based on accuracy, precision, and detection limits, these techniques have been successfully used to analyze lung tissue from a deceased welder, who died, from cancer, and to ...

journal_title：Biological trace element research

authors： Landsberger S,Simsons A

更新日期：1987-08-01 00:00:00

abstract：:Human ocular tissues from 50 donor eyes were elementally and morphologically analyzed in order to correlate the elemental content and distribution of Ca, Ba, Cr, Cu, Zn, and Se with ocular morphology, sex, race, irideal pigmentation, age, time of death, birth weight, presence and severity of diabetes, and other pathol...

journal_title：Biological trace element research

authors： Panessa-Warren BJ,Kraner HW,Jones KW,Kaplan C

更新日期：1987-04-01 00:00:00

abstract：:X-ray fluorescence experiments at the Photon Factory in Japan are described. An energy-dispersive X-ray fluorescence system was combined with various excitation modes, i.e., a continuum and a monochromatic excitation, which consist of a crystal monochromator or a wide band pass monochromator. These excitation modes pr...

journal_title：Biological trace element research

authors： Gohshi Y,Iida A,Matsushita T

更新日期：1987-04-01 00:00:00

abstract：:In order to understand the normal and pathological physiologies of the epidermal cells, the simultaneous determination of several elements in the different cellular strata is of crucial importance. In recent years the electron microprobe (EMP) has become an established technique in this field. Its high spatial resolut...

journal_title：Biological trace element research

authors： Malmqvist KG,Forslind B,Themner K,Hyltén G,Grundin T,Roomans GM

更新日期：1987-04-01 00:00:00

abstract：:Instrumental epithermal neutron activation analysis was used in determining the halide concentration of camel serum. The halides determined were sodium, chloride, bromide, and iodide. Serum was examined when the camels had free access to drinking water, following 10 d of water restriction and 2 h following rapid rehyd...

journal_title：Biological trace element research

authors： Etzion Z,Alfassi Z,Lavi N,Yagil R

更新日期：1987-04-01 00:00:00

abstract：:The forms of Se in the Se-dependent enzyme formate dehydrogenase is known to be selenocysteine, but the way this amino acid enters the polypeptide chain has not been established. Through the use of a cysteine-requiring mutant ofEscherichia coli K-12 that could also grow in the presence of glutathione, we were able to ...

journal_title：Biological trace element research

authors： Karle JA,Shrift A

更新日期：1986-12-01 00:00:00

abstract：:The effect of parenteral zinc on tissue metallothionein (MT) was studied in normal and streptozotocin-induced diabetic rats. The accumulation of Zn-MT in liver and pancreas of normal and diabetic rats following the administration (ip) of various amounts of zinc was not different. Renal Zn-MT was higher in the diabetic...

journal_title：Biological trace element research

authors： Lin LY,McCormick CC

更新日期：1986-12-01 00:00:00

abstract：:The influence of dietary supplementation with thiamine on lead (Pb) contents in blood and tissues, blood δ-aminolevulinic acid dehydratase (δ-ALAD) activity, and urinary excretion of δ-aminolevulinic acid (δ-ALA) was evaluated in male Sprague-Dawley rats. Groups of randomly selected animals were given a thiamine-defic...

journal_title：Biological trace element research

authors： Flora SJ,Sharma RP

更新日期：1986-08-01 00:00:00

abstract：:Calcium, magnesium, and zinc balances were determined in eleven young adult college females (mean age, 24.9±2.35) during a 39-d metabolic study when the subjects were fed an adequate calorie and protein diet based on habitually consumed foods. Analysis showed that the dietary contribution of calcium, magnesium, and zi...

journal_title：Biological trace element research

authors： Atinmo T,Friday M

更新日期：1985-11-01 00:00:00

abstract：:The levels of iron, zinc, and copper in the tissues of the pregnant rat, on d 12, 19, and 21 after impregnation have been determined and compared with controls. Iron levels decreased considerably in late pregnancy as a result of increased fetal requirements, thus diminishing iron stores in rat tissues, but maintaining...

journal_title：Biological trace element research

authors： Mas A,Romeu A,Alemany M,Arola L

更新日期：1985-09-01 00:00:00

abstract：:A series of experiments was conducted to study the effects of dietary and injected lead (as Pb acetate-3H2O) and of dietary Cd, Hg, and Se on fatty acid composition of serum lipids of chicks as measured by gas-liquid chromatography. The effect of dietary Pb on fatty acid composition of erythrocyte membranes was measur...

journal_title：Biological trace element research

authors： Donaldson WE

更新日期：1985-06-01 00:00:00

abstract：:Two 42-d experiments were conducted with weanling male rats to study interactions between nickel and copper. In Experiment 1, a low-copper basal diet was supplemented with copper at 0 or 30 ppm and nickel at 0 or 30 ppm. Copper was added in Experiment 2 to a basal copper-deficient diet at a level of 0 or 15 ppm and ni...

journal_title：Biological trace element research

authors： Spears JW,Hatfield EE

更新日期：1985-04-01 00:00:00

abstract：:The effect ofin utero zinc deficiency on fetal development in rats is reviewed. Attention is paid to the primary biochemical lesion associated with zinc-related teratogenesis and special consideration is given to the central nervous system. Evidence is presented that the thymidine kinase salvage pathway, used for the ...

journal_title：Biological trace element research

authors： Dreosti IE,Record IR,Manuel SJ

更新日期：1985-03-01 00:00:00

abstract：:Wistar male rats were exposed to nickel oxide (NiO) aerosols (mass median aerodynamic diameter, 1.2 μm). The average exposure concentration was controlled from low level (0.6 mg/m(3)) to high level (8.0 mg/m(3)) and total exposure time ranged from 140 to 216 h. Some rats were sacrificed just after the exposure, wherea...

journal_title：Biological trace element research

authors： Kodama Y,Ishimatsu S,Matsuno K,Tanaka I,Tsuchiya K

更新日期：1985-02-01 00:00:00

abstract：:Plasma chromium concentrations have been determined for 150 patients. These were subjected to coronary artery cineangiography and thereby divided into three groups: group CAD (those with coronary artery disease), group HD (those with heart disease, but no CAD) and group N (those with no CAD and no HD). Weighted, avera...

journal_title：Biological trace element research

authors： Simonoff M,Llabador Y,Hamon C,Peers AM,Simonoff GN

更新日期：1984-10-01 00:00:00

abstract：:Glucose metabolism is altered after trauma and those factors that affect glucose metabolism often affect chromium (Cr) metabolism and excretion. To ascertain whether urinary Cr excretion is affected by the elevated serum glucose and other factors associated with trauma, the serum glucose and urinary Cr and Creatinine ...

journal_title：Biological trace element research

authors： Borel JS,Majerus TC,Polansky MM,Moser PB,Anderson RA

更新日期：1984-08-01 00:00:00

abstract：:The purpose of the present study was to measure the pattern of uptake of(75)Se into proteins in normal rat lenses and into the proteins of lenses with selenite-induced cataract. Ten-day-old suckling rats received a single injection of(75)Se with or without a cataractous dose of cold carrier sodium selenite. Four days ...

journal_title：Biological trace element research

authors： Shearer TR,Ridlington JW,Goeger DE,Whanger PD

更新日期：1984-06-01 00:00:00

abstract：:Although substantial progress has been achieved in inductovely coupled plasma (ICP) spectroscopy, placing it among the principal spectroscopic tools in analytical chemistry research and applications laboratories, some limitations exist especially for the analysis of ultratrace concentration levels in biological materi...

journal_title：Biological trace element research

authors： Barnes RM

更新日期：1984-02-01 00:00:00

abstract：:The movement of copper and zinc from the fertilized egg into the developing embryo and the subsequent association of the two metals with metallothionein-like proteins (MT) of chick liver was investigated. Hepatic levels of MT in 1-d-old chicks, estimated from specifically bound(115m)Cd, were increased eightfold over e...

journal_title：Biological trace element research

authors： Sandrock BC,Kern SR,Bryan SE

更新日期：1983-12-01 00:00:00